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Effects of Atrazine on Estrogen Receptor

Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts Objectives: We aimed to evaluate the potential of atrazine to trigger GPER-mediated signaling in cancer cells and cancer-associated fibroblasts (CAFs). Scarica l’Articolo

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GPER signalling in both cancer

GPER signalling in both cancerassociated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response Cancer-associated fibroblasts (CAFs) as main players within the tumor microenvironment contribute to the growth, expansion and dissemination of cancer cells. For instance, CAFs generate a dynamic signalling network through the secretion of several factors that …

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