Bisphenol A Induces Gene Expression Changes

Bisphenol A Induces Gene Expression Changes and Proliferative Effects through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts Bisphenol A (BPA), used largely in the manufacture of polycarbonate plastics, is the constituent of a wide array of consumer products, including plastic food containers, baby bottles, and the lining of metal food cans (Welshons et al. 2006). …

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GPER mediates the Egr-1 expression induced by 17β-estradiol

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4- hydroxitamoxifen in breast and endometrial cancer cells Early growth response-1 (Egr-1) is an immediate early gene involved in relevant biological events including the proliferation of diverse types of cell tumors. In a microarray analysis performed in breast cancer cells, 17β-estradiol (E2) and the …

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GPER mediates the Egr-1 expression induced by 17β-estradiol

GPER mediates the Egr-1 expression induced by 17β-estradiol and 4- hydroxitamoxifen in breast and endometrial cancer cells Abstract Early growth response-1 (Egr-1) is an immediate early gene involved in relevant biological events including the proliferation of diverse types of cell tumors. In a microarray analysis performed in breast cancer cells, …

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G-Protein–Coupled Receptor 30 and Estrogen Receptor-α

G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells BACKGROUND: Atrazine, one of the most common pesticide contaminants, has been shown to up-regulate aromatase activity in certain estrogen-sensitive tumors without binding or activating the estrogen receptor (ER). Recent investigations have …

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